Résumé for John Terhorst
Research in Monte Carlo statistical perturbation theory for computing free-energy binding affinities using implicit solvent models, including software design and implementation.
Development of molecular mechanics force fields including explicit treatment of polarization effects for use in computer-aided drug design of therapeutic agents targeting infectious, inflammatory, and hyperproliferative diseases.
Seventeen years experience in instruction of chemistry, including organic chemistry and spectroscopy lecture and lab courses, as a teaching assistant, private tutor, graduate teaching fellow, and university professor.
Adjunct Assistant Professor of Chemistry
Costa Mesa, California
April, 2012 to present
Adjunct Professor of Chemistry
University of Redlands
August, 2020 to present
Private Chemistry Tutor
October, 2012 to present
1400+ Lessons, 400+ Ratings
2006 to 2011
2006 to 2008
University of Redlands
2002 to 2006
University of Redlands
2002 to 2006
Teaching and Tutoring ExperiencePrivate Tutor: Introductory, Honors, A.P., General, and Organic Chemistry
I have helped students from the following schools and universities succeed at chemistry:
Yale University, Stanford University, Dartmouth College, Tulane University, UNC Chapel Hill, Texas A&M University, University of Miami, University of Delaware, Vanderbilt University, Boston University, University of Kentucky, Phillips Andover Academy, UC Irvine, UC Riverside, University of Southern California, University of Redlands, La Sierra University, Chapman University, Cal State Fullerton, Furman University, Saddleback College, Irvine Valley College, University High School, Newport Beach High School, Woodbridge High School, San Juan Hills High School, Corona del Mar High School, Yorba Linda High School, Mater Dei High School, Troy High School, Cornelia Connelly School, Sage Hill School, Deerfield Academy, Fairmont Preparatory Academy.
Vanguard University of Southern California
CHEM 485: Research Topics in Chemistry. Computational, theoretical, and physical organic chemistry.
CHEM 455: Chemistry Teaching Internship. Oversight of students planning and conducting a lecture, recitation, and/or laboratory course.
CHEM 308: Introduction to Spectroscopy. Includes IR spectroscopy, 1H and 13C NMR spectroscopy, mass spectrometry, and UV/vis spectrophotometry.
CHEM 304/305: Organic Chemistry I/II. Functional groups, nomenclature, stereochemistry, aromaticity, reaction mechanisms, and molecular orbital theory.
CHEM 120/121: General Chemistry I/II. Atomic structure, bonding, stoichiometry, and reactions; kinetics, equilibrium, thermodynamics, and electrochemistry.
CHEM 113: Fundamentals of General, Organic, and Biochemistry II. Foundational principles, functional groups, simple organic reactions, carbohydrates, lipids, protein synthesis, nucleic acids, and biochemical applications.
CHEM 112C: Fundamentals of General, Organic, and Biochemistry I. Atomic theory, periodic trends, measurements, stoichiometry, chemical reactions and equilibrium, and acids and bases.
CHEM 222/223: Organic Chemistry Lab I/II. Reflux, TLC, recrystallization, column chromatography, extraction, Grignard chemistry, Williamson ether synthesis, aldol and Claisen condensations, and sodium borohydride reduction.
CHEM 221: Organic Chemistry of Life Processes. A continuation of Introductory Organic Chemistry, covering reactivity and mechanisms in organic chemistry with an emphasis in their various roles in biological processes.
CHEM 220: Introductory Organic Chemistry. The first semester in a two-semester sequence offers a comprehensive look at the fundamental principles of organic chemistry. Offered off-sequence for students on an accelerated track.
CHEM 114: General Chemistry I. A survey of modern descriptive, inorganic, and physical chemistry. Topics included atomic theory, stoichiometry, thermochemistry, chemical periodicity, concepts in chemical bonding, and the shapes of molecules.
University of Redlands
CHEM 231/232: Organic Chemistry I/II. A two-semester sequence offering a comprehensive survey of the chemistry of carbon-containing compounds, their structure, nomenclature, physical properties, spectroscopy (IR, GC-MS, NMR), stereochemistry, chemical reactivities, reaction mechanisms, and synthesis.
CHEM 131/132: General Chemistry I/II. A two-semester sequence covering stoichiometry and modern views of the properties, structure, and reactivity of atoms and molecules.
CHEM 102: Chemistry and the Environment. Introductory course for students wishing to explore the science or needing preparation for General Chemistry. Topics in chemistry relevant to the environment, such as energy needs, pollution, and pesticides.
Honors, Awards, and Fellowships
Dox Research Fellowship, Yale University, 2009
The Dox Fellowship was established to provide stipend support to graduate students in the field of organic chemistry, given in recognition of excellence in academics and research.
Distinguished Chemistry Fellowship, Yale University, 2006-2011
Graduate students of exceptional promise are awarded the Distinguished Chemistry Fellowship for five years of stipend support while conducting research towards the completion of a doctorate in chemistry.
Graduate Summa cum Laude, University of Redlands, 2006
Latin honors of summa cum laude are conferred upon graduating seniors who possess a cumulative GPA of 3.85 or higher.
Phi Beta Kappa, Xi Chapter of Southern California, 2006
Graduating seniors at the University of Redlands are inducted into PBK in recognition of excellence in the liberal arts and sciences.
Robert D. Engel Award, University of Redlands, 2006
The Robert D. Engel award is given to the outstanding senior science major at the University of Redlands.
Edmund C. Jaeger Award, University of Redlands, 2005
The Edmund C. Jaeger award is given by the University of Redlands for exceptional scholarship to a junior male biology student planning a career in teaching or research.
Tutor of the Year, University of Redlands, 2005
The title of Tutor of the Year is given in recognition of a tutor's valuable contributions to the University of Redlands' Tutoring Center.
Research ExperienceDirector, Summer Undergraduate Research Program, Vanguard University, 2015
Research Advisor, Computational Chemistry, Vanguard University, 2013-2016, 2018
Studies of pure liquids, conformational dynamics, and molecular design of anti-HIV agents.
Advisees: Chris Bridges (B.S., 2014), Justin Pugh (B.S., 2014), Josiah Morales (B.S., 2014), Brennan Gregory (B.S., 2016), Chalane Records (B.S., 2015), Ashley Harris (B.S., 2016), Israel Sanchez (B.S., 2016), Emily Eggleston (B.S., 2018), Mia Kilekas (B.S., 2018), and Kacie Quiñones, (B.S., 2019).
Graduate Student, Chemical Theory and Computation, Yale University, 2007-2011
Conformational dynamics, molecular mechanical force field parameters, and new methods for computing free energies of binding using continuum solvent models in a Monte Carlo manifold.
Advisor: William L. Jorgensen.
Undergraduate Student, Organic Chemistry, University of Redlands, 2004-2006
The [3+2] cycloaddition of carbonyl oxides in the synthesis of 1,2-dioxolanes, preparation of carbonyl oxides from precursors other than primary ozonides, and total synthesis of jasmine ketolactone.
Advisor: David P. Soulsby.
Undergraduate Student, Theoretical Chemistry, University of Redlands, 2003-2004
Theoretical investigations of photopumping in doubly illuminated liquid membranes containing photoactive carriers.
Advisor: Teresa Longin.
E/Z Energetics for Molecular Modeling and Design.
J. Terhorst and W. L. Jorgensen
J. Chem. Theory Comput. 2010, 6:9, 2762-2769. doi:10.1021/ct1004017
Simulations of Photopumping in Doubly Illuminated Liquid Membranes Containing Photoactive Carriers.
T. L. Longin, J. Terhorst, and C. Lang
J. Phys. Chem. B 2010, 114:48 15846-15858. doi:10.1021/jp106802q
Continuum Solvent Models and Force Field Development in Computer-Aided Drug Design.
Terhorst, J., Ph.D. Dissertation, Yale University, 2011. ProQuest UMI-3496989
An Efficient Method for Calculating Born Energies with the GB/SA Solvation Model in Monte Carlo Simulations.
Terhorst, J., Thesis Prospectus, Yale University, 2008.
Theoretical Studies of Photopumping in Photofacilitated Liquid Membranes and The [3+2] Cycloaddition of Carbonyl Oxides in the Synthesis of 1,2-Dioxolanes.
Terhorst, J., Honors Thesis, University of Redlands, 2006.